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Two contradictory, unexpected events bring Alice and Jack even closer and lead them to reflect on their past and imagine a future, as the show nears an end. 

The Post Office and its Horizon computer system have caused not just financial and reputational damage to former employees but psychological. An independent investigation begins to look into the failures.

A young couple underestimates their ability to be responsible parents, but they are put to the test by a medical issue in both their daughters. The Turners face their own trouble with one of their children. 

After Alice makes Jack rich, she once again disappears from his life until his daughter seeks her out for answers. Then Alice and Jack are able to simply be friends –  at least for now. 

A computer system causes issues at post offices across the UK, but the post office refuses to acknowledge them and instead blames subpostmasters, making them pay to make up "lost" money.

A distraction at home leads Trixie to rush while working with a patient with the pupil midwife Joyce, while other midwives help a Nigerian family with tuberculosis.

An unexpected invitation upsets Jack and leads him to once again reconnect with Alice. Later, she offers him an opportunity to make a fortune. 

Nolly returns to the stage after decades and worries about failing, before eventually making a valedictory return to the show that made her famous. 

Violet is running for mayor with the support of her family and friends, but a medical emergency threatens to derail her life first.

Jack's new marriage to Lynn is upset by the reappearance of Alice in his life, while Alice makes a startling admission about her past. 

As Nolly and everyone else are desperate to learn how her character will be killed off, she also worries about what she will do once her contract ends. 

Cyril and the midwives help a woman whose husband has left her with one child and another on the way and whose government housing is infected with mold.

Alice and Jack's romance is brief but intense, and leaves indelible marks on both as they continue to move through life. 

Noele Gordon has been the star of a popular soap opera for eighteen years when she learns that she is being fired, for no apparent reason.

A new set of midwife pupils arrives in Poplar and one of them is immediately thrust into danger, while the other midwives aid a mother with cerebral palsy.